1I90
CARBONIC ANHYDRASE II COMPLEXED WITH AL-8520 2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE, 4-AMINO-3,4-DIHYDRO-2-(3-METHOXYPROPYL)-, 1,1-DIOXIDE, (R)
Summary for 1I90
Entry DOI | 10.2210/pdb1i90/pdb |
Related | 1I8z 1I91 |
Descriptor | CARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | carbonic anhydrase ii, al-8520, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29777.30 |
Authors | Kim, C.-Y.,Chang, J.S.,Liao, J.,May, J.A.,Christianson, D.W. (deposition date: 2001-03-16, release date: 2001-03-28, Last modification date: 2024-02-07) |
Primary citation | Kim, C.Y.,Whittington, D.A.,Chang, J.S.,Liao, J.,May, J.A.,Christianson, D.W. Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IV. J.Med.Chem., 45:888-893, 2002 Cited by PubMed: 11831900DOI: 10.1021/jm010163d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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