1I85
CRYSTAL STRUCTURE OF THE CTLA-4/B7-2 COMPLEX
Summary for 1I85
Entry DOI | 10.2210/pdb1i85/pdb |
Descriptor | T LYMPHOCYTE ACTIVATION ANTIGEN CD86, CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4 (2 entities in total) |
Functional Keywords | ig v-type domain, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P42081 P16410 |
Total number of polymer chains | 4 |
Total formula weight | 52719.94 |
Authors | Schwartz, J.-C.D.,Zhang, X.,Fedorov, A.A.,Nathenson, S.G.,Almo, S.C. (deposition date: 2001-03-12, release date: 2001-04-04, Last modification date: 2011-07-13) |
Primary citation | Schwartz, J.C.,Zhang, X.,Fedorov, A.A.,Nathenson, S.G.,Almo, S.C. Structural basis for co-stimulation by the human CTLA-4/B7-2 complex. Nature, 410:604-608, 2001 Cited by PubMed: 11279501DOI: 10.1038/35069112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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