1I1P

REFINEMENT INCLUDING EXPERIMENTAL MAD PHASES ALLOWS AN EXHAUSTIVE STUDY OF ORDERED SOLVENT MOLECULES FOR A PLATINATED DECANUCLEOTIDE

Summary for 1I1P

• Entry DOI: 10.2210/pdb1i1p/pdb
• Descriptor: 5'-D(*CP*CP*TP*CP*GP*CP*TP*CP*TP*C)-3', 5'-D(*GP*AP*GP*AP*GP*CP*GP*AP*GP*G)-3', Cisplatin, ... (5 entities in total)
• Functional Keywords: antitumor drug, cis-ddp, interstrand cross-link, deoxyribonucleic acid, spermine, dna
• Total number of polymer chains: 2
• Total formula weight: 6593.38

Authors

Coste, F.,Shepard, W.,Zelwer, C. (deposition date: 2001-02-02, release date: 2002-06-21, Last modification date: 2024-02-07)

• Primary citation: Coste, F.,Shepard, W.,Zelwer, C.; Description of ordered solvent molecules in a platinated decanucleotide duplex refined at 1.6A resolution against experimental MAD phases.; Acta Crystallogr.,Sect.D, 58:431-440, 2002; PubMed: 11856828; DOI: 10.1107/S0907444901021709

Experimental method

X-RAY DIFFRACTION (1.63 Å)