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1HWV

MOLECULAR TOPOLOGY OF POLYCYCLIC AROMATIC CARCINOGENS DETERMINES DNA ADDUCT CONFORMATION: A LINK TO TUMORIGENIC ACTIVITY

Summary for 1HWV
Entry DOI10.2210/pdb1hwv/pdb
Related1HX4
Descriptor5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3', (1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL (3 entities in total)
Functional Keywordscarcinogen-dna adduct, benzo[c]phenanthrene dna adduct, dna
Total number of polymer chains2
Total formula weight6988.71
Authors
Patel, D.J.,Lin, C.H.,Geacintov, N.E.,Broyde, S.,Huang, X.,Kolbanovskii, A.,Hingerty, B.E.,Amin, S. (deposition date: 2001-01-10, release date: 2001-03-21, Last modification date: 2022-02-23)
Primary citationLin, C.H.,Huang, X.,Kolbanovskii, A.,Hingerty, B.E.,Amin, S.,Broyde, S.,Geacintov, N.E.,Patel, D.J.
Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
J.Mol.Biol., 306:1059-1080, 2001
Cited by
PubMed: 11237618
DOI: 10.1006/jmbi.2001.4425
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

數據於2024-03-27公開中

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