1HWV
MOLECULAR TOPOLOGY OF POLYCYCLIC AROMATIC CARCINOGENS DETERMINES DNA ADDUCT CONFORMATION: A LINK TO TUMORIGENIC ACTIVITY
Summary for 1HWV
Entry DOI | 10.2210/pdb1hwv/pdb |
Related | 1HX4 |
Descriptor | 5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3', (1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL (3 entities in total) |
Functional Keywords | carcinogen-dna adduct, benzo[c]phenanthrene dna adduct, dna |
Total number of polymer chains | 2 |
Total formula weight | 6988.71 |
Authors | Patel, D.J.,Lin, C.H.,Geacintov, N.E.,Broyde, S.,Huang, X.,Kolbanovskii, A.,Hingerty, B.E.,Amin, S. (deposition date: 2001-01-10, release date: 2001-03-21, Last modification date: 2024-05-22) |
Primary citation | Lin, C.H.,Huang, X.,Kolbanovskii, A.,Hingerty, B.E.,Amin, S.,Broyde, S.,Geacintov, N.E.,Patel, D.J. Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity. J.Mol.Biol., 306:1059-1080, 2001 Cited by PubMed: 11237618DOI: 10.1006/jmbi.2001.4425 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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