1HWT

STRUCTURE OF A HAP1/DNA COMPLEX REVEALS DRAMATICALLY ASYMMETRIC DNA BINDING BY A HOMODIMERIC PROTEIN

1HWT の概要

• エントリーDOI: 10.2210/pdb1hwt/pdb
• 分子名称: DNA (5'-D(*GP*CP*GP*CP*TP*AP*TP*TP*AP*TP*CP*GP*CP*TP*AP*TP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*AP*TP*AP*GP*CP*GP*AP*TP*AP*AP*TP*AP*GP*CP*GP*C)-3'), PROTEIN (HEME ACTIVATOR PROTEIN), ... (5 entities in total)
• 機能のキーワード: transcription factor, asymmetry, gal4, complex activator-dna, gene regulation-dna complex, gene regulation/dna
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 63628.22

構造登録者

King, D.A.,Zhang, L.,Guarente, L.,Marmorstein, R. (登録日: 1998-09-17, 公開日: 1999-11-10, 最終更新日: 2024-04-03)

• 主引用文献: King, D.A.,Zhang, L.,Guarente, L.,Marmorstein, R.; Structure of a HAP1-DNA complex reveals dramatically asymmetric DNA binding by a homodimeric protein.; Nat.Struct.Biol., 6:64-71, 1999; PubMed: 9886294; DOI: 10.1038/4940

実験手法

X-RAY DIFFRACTION (2.5 Å)