1HVQ

CRYSTAL STRUCTURES OF HEVAMINE, A PLANT DEFENCE PROTEIN WITH CHITINASE AND LYSOZYME ACTIVITY, AND ITS COMPLEX WITH AN INHIBITOR

Summary for 1HVQ

Entry DOI	10.2210/pdb1hvq/pdb
Related PRD ID	PRD_900017
Descriptor	HEVAMINE A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	glycosidase, chitin degradation, multifunctional enzyme, hydrolase
Biological source	Hevea brasiliensis
Cellular location	Vacuole: P23472
Total number of polymer chains	1
Total formula weight	30200.78
Authors	Terwisscha Van Scheltinga, A.C.,Kalk, K.H.,Beintema, J.J.,Dijkstra, B.W. (deposition date: 1994-10-13, release date: 1995-12-02, Last modification date: 2024-10-09)
Primary citation	Terwisscha van Scheltinga, A.C.,Kalk, K.H.,Beintema, J.J.,Dijkstra, B.W. Crystal structures of hevamine, a plant defence protein with chitinase and lysozyme activity, and its complex with an inhibitor. Structure, 2:1181-1189, 1994 Cited by PubMed Abstract: Hevamine is a member of one of several families of plant chitinases and lysozymes that are important for plant defence against pathogenic bacteria and fungi. The enzyme can hydrolyze the linear polysaccharide chains of chitin and peptidoglycan. A full understanding of the structure/function relationships of chitinases might facilitate the production of transgenic plants with increased resistance towards a wide range of pathogens. PubMed: 7704528 DOI: 10.1016/S0969-2126(94)00120-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation