1HT2

Nucleotide-Dependent Conformational Changes in a Protease-Associated ATPase HslU

1HT2 の概要

• エントリーDOI: 10.2210/pdb1ht2/pdb
• 関連するPDBエントリー: 1DOO 1E94 1HQY 1HT1
• 分子名称: HEAT SHOCK LOCUS HSLV, HEAT SHOCK LOCUS HSLU, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
• 機能のキーワード: hslvu, peptidase-atpase complex, chaperone
• 由来する生物種: Escherichia coli; 詳細
• 細胞内の位置: Cytoplasm: P0A7B8 P0A6H5
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 355584.06

構造登録者

Wang, J.,Song, J.J.,Seong, I.S.,Franklin, M.C.,Kamtekar, S.,Eom, S.H.,Chung, C.H. (登録日: 2000-12-27, 公開日: 2001-11-14, 最終更新日: 2024-02-07)

主引用文献

Wang, J.,Song, J.J.,Seong, I.S.,Franklin, M.C.,Kamtekar, S.,Eom, S.H.,Chung, C.H.
Nucleotide-dependent conformational changes in a protease-associated ATPase HsIU.
Structure, 9:1107-1116, 2001

PubMed Abstract: The bacterial heat shock locus ATPase HslU is an AAA(+) protein that has structures known in many nucleotide-free and -bound states. Nucleotide is required for the formation of the biologically active HslU hexameric assembly. The hexameric HslU ATPase binds the dodecameric HslV peptidase and forms an ATP-dependent HslVU protease.

PubMed: 11709174
DOI: 10.1016/S0969-2126(01)00670-0

実験手法

X-RAY DIFFRACTION (2.8 Å)