1HRD

GLUTAMATE DEHYDROGENASE

1HRD の概要

• エントリーDOI: 10.2210/pdb1hrd/pdb
• 分子名称: GLUTAMATE DEHYDROGENASE (2 entities in total)
• 機能のキーワード: oxidoreductase, nad
• 由来する生物種: Clostridium symbiosum
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 147646.94

構造登録者

Britton, K.L.,Baker, P.J.,Stillman, T.J.,Rice, D.W. (登録日: 1996-04-03, 公開日: 1997-03-12, 最終更新日: 2024-02-07)

主引用文献

Yip, K.S.,Stillman, T.J.,Britton, K.L.,Artymiuk, P.J.,Baker, P.J.,Sedelnikova, S.E.,Engel, P.C.,Pasquo, A.,Chiaraluce, R.,Consalvi, V.,Scandurra, R.,Rice, D.W.
The structure of Pyrococcus furiosus glutamate dehydrogenase reveals a key role for ion-pair networks in maintaining enzyme stability at extreme temperatures.
Structure, 3:1147-1158, 1995

PubMed Abstract: The hyperthermophile Pyrococcus furiosus is one of the most thermostable organisms known, with an optimum growth temperature of 100 degrees C. The proteins from this organism display extreme thermostability. We have undertaken the structure determination of glutamate dehydrogenase from P. furiosus in order to gain further insights into the relationship between molecular structure and thermal stability.

PubMed: 8591026
DOI: 10.1016/S0969-2126(01)00251-9

実験手法

X-RAY DIFFRACTION (1.96 Å)