1HR2

CRYSTAL STRUCTURE ANALYSIS OF A MUTANT P4-P6 DOMAIN (DELC209) OF TETRAHYMENA THEMOPHILA GROUP I INTRON.

1HR2 の概要

• エントリーDOI: 10.2210/pdb1hr2/pdb
• 関連するPDBエントリー: 1gid
• 分子名称: P4-P6 DELC209 MUTANT RNA RIBOZYME DOMAIN, MAGNESIUM ION (3 entities in total)
• 機能のキーワード: rna, p4-p6, c209, ribozyme, tetrahymena, group i intron, ribonucleic acid
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 103203.51

構造登録者

Juneau, K.,Podell, E.R.,Harrington, D.J.,Cech, T.R. (登録日: 2000-12-20, 公開日: 2001-04-12, 最終更新日: 2023-08-09)

主引用文献

Juneau, K.,Podell, E.,Harrington, D.J.,Cech, T.R.
Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions.
Structure, 9:221-231, 2001

PubMed Abstract: The structure of P4-P6, a 160 nucleotide domain of the self-splicing Tetrahymena thermophila intron, was solved previously. Mutants of the P4-P6 RNA that form a more stable tertiary structure in solution were recently isolated by successive rounds of in vitro selection and amplification.

PubMed: 11286889
DOI: 10.1016/S0969-2126(01)00579-2

実験手法

X-RAY DIFFRACTION (2.25 Å)