1HOV

SOLUTION STRUCTURE OF A CATALYTIC DOMAIN OF MMP-2 COMPLEXED WITH SC-74020

1HOV の概要

分子名称MATRIX METALLOPROTEINASE-2, ZINC ION, CALCIUM ION, ... (4 entities in total)
機能のキーワードenzyme-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
由来する生物種Homo sapiens (human)
細胞内の位置Secreted, extracellular space, extracellular matrix P08253
ポリマー鎖数1
分子量合計19277.1
構造登録者
主引用文献
Feng, Y.,Likos, J.J.,Zhu, L.,Woodward, H.,Munie, G.,McDonald, J.J.,Stevens, A.M.,Howard, C.P.,De Crescenzo, G.A.,Welsch, D.,Shieh, H.-S.,Stallings, W.C.
Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor
Biochim.Biophys.Acta, 1598:10-23, 2002
PubMed: 12147339 (主引用文献が同じPDBエントリー)
DOI: 10.1016/S0167-4838(02)00307-2
MImport into Mendeley
実験手法
SOLUTION NMR
NMR情報
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliers6211.2%33.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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