1HOV

SOLUTION STRUCTURE OF A CATALYTIC DOMAIN OF MMP-2 COMPLEXED WITH SC-74020

1HOV の概要

• エントリーDOI: 10.2210/pdb1hov/pdb
• 分子名称: MATRIX METALLOPROTEINASE-2, ZINC ION, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: enzyme-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted, extracellular space, extracellular matrix: P08253
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19277.10

構造登録者

Feng, Y.,Likos, J.J.,Zhu, L.,Woodward, H.,Munie, G.,McDonald, J.J.,Stevens, A.M.,Howard, C.P.,De Crescenzo, G.A.,Welsch, D.,Shieh, H.-S.,Stallings, W.C. (登録日: 2000-12-11, 公開日: 2001-12-12, 最終更新日: 2022-02-23)

• 主引用文献: Feng, Y.,Likos, J.J.,Zhu, L.,Woodward, H.,Munie, G.,McDonald, J.J.,Stevens, A.M.,Howard, C.P.,De Crescenzo, G.A.,Welsch, D.,Shieh, H.-S.,Stallings, W.C.; Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor; Biochim.Biophys.Acta, 1598:10-23, 2002; PubMed: 12147339; DOI: 10.1016/S0167-4838(02)00307-2

実験手法

SOLUTION NMR