1HNI

STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION

1HNI の概要

分子名称HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), (2-ACETYL-5-METHYLANILINO)(2,6-DIBROMOPHENYL)ACETAMIDE (3 entities in total)
機能のキーワードnucleotidyltransferase
由来する生物種Human immunodeficiency virus 1
細胞内の位置Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential) P03366 P03367
ポリマー鎖数2
分子量合計114624.06
構造登録者
Ding, J.,Das, K.,Arnold, E. (登録日: 1995-02-28, 公開日: 1995-06-03, 最終更新日: 2012-02-22)
主引用文献
Ding, J.,Das, K.,Tantillo, C.,Zhang, W.,Clark Jr., A.D.,Jessen, S.,Lu, X.,Hsiou, Y.,Jacobo-Molina, A.,Andries, K.,Pauwels, R.,Moereels, H.,Koymans, L.,Janssen, P.A.J.,Smith Jr., R.H.,Koepke, M.K.,Michejda, C.J.,Hughes, S.H.,Arnold, E.
Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution.
Structure, 3:365-379, 1995
PubMed: 7542140 (主引用文献が同じPDBエントリー)
DOI: 10.1016/S0969-2126(01)00168-X
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.8 Å)
NMR情報
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers411.8%8.8%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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