1HM9

CRYSTAL STRUCTURE OF S.PNEUMONIAE N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE, GLMU, BOUND TO ACETYL COENZYME A AND UDP-N-ACETYLGLUCOSAMINE

1HM9 の概要

• エントリーDOI: 10.2210/pdb1hm9/pdb
• 関連するPDBエントリー: 1FWY 1FXJ 1HM0 1HM8
• 分子名称: UDP-N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE, CALCIUM ION, ACETYL COENZYME *A, ... (5 entities in total)
• 機能のキーワード: acetyltransferase, bifunctional, drug design, pyrophosphorylase, rossmann-like fold, left-handed-beta-helix, trimer, domain-interchange, transferase
• 由来する生物種: Streptococcus pneumoniae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 104233.68

構造登録者

Sulzenbacher, G.,Gal, L.,Peneff, C.,Fassy, F.,Bourne, Y. (登録日: 2000-12-05, 公開日: 2001-11-30, 最終更新日: 2023-08-09)

• 主引用文献: Sulzenbacher, G.,Gal, L.,Peneff, C.,Fassy, F.,Bourne, Y.; Crystal structure of Streptococcus pneumoniae N-acetylglucosamine-1-phosphate uridyltransferase bound to acetyl-coenzyme A reveals a novel active site architecture.; J.Biol.Chem., 276:11844-11851, 2001; PubMed: 11118459; DOI: 10.1074/jbc.M011225200

実験手法

X-RAY DIFFRACTION (1.75 Å)