1HJP

HOLLIDAY JUNCTION BINDING PROTEIN RUVA FROM E. COLI

1HJP の概要

• エントリーDOI: 10.2210/pdb1hjp/pdb
• 分子名称: RUVA (2 entities in total)
• 機能のキーワード: dna recombination, dna repair, holliday junction binding
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22111.67

構造登録者

Nishino, T.,Ariyoshi, M.,Iwasaki, H.,Shinagawa, H.,Morikawa, K. (登録日: 1997-08-21, 公開日: 1998-02-25, 最終更新日: 2024-02-07)

主引用文献

Nishino, T.,Ariyoshi, M.,Iwasaki, H.,Shinagawa, H.,Morikawa, K.
Functional Analyses of the Domain Structure in the Holliday Junction Binding Protein Ruva
Structure, 6:11-21, 1998

PubMed Abstract: Homologous recombination is crucial for genetic diversity and repairing damaged chromosomes. In Escherichia coli cells, the RuvA, RuvB and RuvC proteins participate in the processing of an important intermediate, the Holliday junction. The RuvA-RuvB protein complex facilitates branch migration of the junction, depending on ATP hydrolysis. The atomic structure of RuvA should enable critical questions to be addressed about its specific interactions with the Holliday junction and the RuvB protein.

PubMed: 9493263
DOI: 10.1016/S0969-2126(98)00003-3

実験手法

X-RAY DIFFRACTION (2.5 Å)