1HIB
THE STRUCTURE OF AN INTERLEUKIN-1 BETA MUTANT WITH REDUCED BIOACTIVITY SHOWS MULTIPLE SUBTLE CHANGES IN CONFORMATION THAT AFFECT PROTEIN-PROTEIN RECOGNITION
Summary for 1HIB
Entry DOI | 10.2210/pdb1hib/pdb |
Descriptor | INTERLEUKIN-1 BETA (2 entities in total) |
Functional Keywords | cytokine |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 17351.78 |
Authors | Camacho, N.P.,Smith, D.R.,Goldman, A.,Schneider, B.,Green, D.,Young, P.R.,Berman, H.M. (deposition date: 1993-03-29, release date: 1994-01-31, Last modification date: 2024-02-07) |
Primary citation | Camacho, N.P.,Smith, D.R.,Goldman, A.,Schneider, B.,Green, D.,Young, P.R.,Berman, H.M. Structure of an interleukin-1 beta mutant with reduced bioactivity shows multiple subtle changes in conformation that affect protein-protein recognition. Biochemistry, 32:8749-8757, 1993 Cited by PubMed: 8364024DOI: 10.1021/bi00085a005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report