1HEX

STRUCTURE OF 3-ISOPROPYLMALATE DEHYDROGENASE IN COMPLEX WITH NAD+: LIGAND-INDUCED LOOP-CLOSING AND MECHANISM FOR COFACTOR SPECIFICITY

Summary for 1HEX

Entry DOI	10.2210/pdb1hex/pdb
Descriptor	3-ISOPROPYLMALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
Functional Keywords	oxidoreductase
Biological source	Thermus thermophilus
Cellular location	Cytoplasm: Q5SIY4
Total number of polymer chains	1
Total formula weight	37488.59
Authors	Hurley, J.H. (deposition date: 1994-09-09, release date: 1994-12-20, Last modification date: 2024-02-07)
Primary citation	Hurley, J.H.,Dean, A.M. Structure of 3-isopropylmalate dehydrogenase in complex with NAD+: ligand-induced loop closing and mechanism for cofactor specificity. Structure, 2:1007-1016, 1994 Cited by PubMed: 7881901 DOI: 10.1016/S0969-2126(94)00104-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation