Summary for 1HCL
Related | 1HCK |
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Descriptor | HUMAN CYCLIN-DEPENDENT KINASE 2 (2 entities in total) |
Functional Keywords | transferase, serine/threonine protein kinase, atp-binding, cell cycle, cell division, mitosis, phosphorylation, protein kinase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total molecular weight | 33976.49 |
Authors | Schulze-Gahmen, U.,De Bondt, H.L.,Kim, S.-H. (deposition date: 1996-06-03, release date: 1996-12-07, Last modification date: 2011-07-13) |
Primary citation | Schulze-Gahmen, U.,De Bondt, H.L.,Kim, S.H. High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J.Med.Chem., 39:4540-4546, 1996 PubMed: 8917641 (PDB entries with the same primary citation) DOI: 10.1021/jm960402a ![]() |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |