1HAI

THE ISOMORPHOUS STRUCTURES OF PRETHROMBIN2, HIRUGEN-AND PPACK-THROMBIN: CHANGES ACCOMPANYING ACTIVATION AND EXOSITE BINDING TO THROMBIN

1HAI の概要

• エントリーDOI: 10.2210/pdb1hai/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000020
• 分子名称: ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... (5 entities in total)
• 機能のキーワード: serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34551.95

構造登録者

Tulinsky, A.,Vijayalakshmi, J. (登録日: 1994-06-27, 公開日: 1994-12-20, 最終更新日: 2020-07-29)

• 主引用文献: Vijayalakshmi, J.,Padmanabhan, K.P.,Mann, K.G.,Tulinsky, A.; The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.; Protein Sci., 3:2254-2271, 1994; PubMed: 7756983

実験手法

X-RAY DIFFRACTION (2.4 Å)