1H1K

THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA

Summary for 1H1K

• Entry DOI: 10.2210/pdb1h1k/pdb
• Related: 2BTV
• Descriptor: RNA, ... (6 entities in total)
• Functional Keywords: virus/viral protein/rna, virus, viral protein, rna, virus-viral protein-rna complex
• Biological source: BLUETONGUE VIRUS; More
• Total number of polymer chains: 6
• Total formula weight: 605238.24

Authors

Diprose, J.M.,Grimes, J.M.,Sutton, G.C.,Burroughs, J.N.,Meyer, A.,Maan, S.,Mertens, P.P.C.,Stuart, D.I. (deposition date: 2002-07-17, release date: 2002-09-26, Last modification date: 2024-05-08)

Primary citation

Diprose, J.M.,Grimes, J.M.,Sutton, G.C.,Burroughs, J.N.,Meyer, A.,Maan, S.,Mertens, P.P.C.,Stuart, D.I.
The Core of Bluetongue Virus Binds Double-Stranded RNA
J.Virol., 76:9533-, 2002

PubMed Abstract: Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.

PubMed: 12186935
DOI: 10.1128/JVI.76.18.9533-9536.2002

Experimental method

X-RAY DIFFRACTION (10 Å)