1H1K

THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA

1H1K の概要

• エントリーDOI: 10.2210/pdb1h1k/pdb
• 関連するPDBエントリー: 2BTV
• 分子名称: RNA, ... (6 entities in total)
• 機能のキーワード: virus/viral protein/rna, virus, viral protein, rna, virus-viral protein-rna complex
• 由来する生物種: BLUETONGUE VIRUS; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 605238.24

構造登録者

Diprose, J.M.,Grimes, J.M.,Sutton, G.C.,Burroughs, J.N.,Meyer, A.,Maan, S.,Mertens, P.P.C.,Stuart, D.I. (登録日: 2002-07-17, 公開日: 2002-09-26, 最終更新日: 2024-05-08)

主引用文献

Diprose, J.M.,Grimes, J.M.,Sutton, G.C.,Burroughs, J.N.,Meyer, A.,Maan, S.,Mertens, P.P.C.,Stuart, D.I.
The Core of Bluetongue Virus Binds Double-Stranded RNA
J.Virol., 76:9533-, 2002

PubMed Abstract: Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.

PubMed: 12186935
DOI: 10.1128/JVI.76.18.9533-9536.2002

実験手法

X-RAY DIFFRACTION (10 Å)