1GZ4

molecular mechanism of the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate

Summary for 1GZ4

• Entry DOI: 10.2210/pdb1gz4/pdb
• Related: 1DO8 1EFK 1EFL 1GZ3 1QR6
• Descriptor: NAD-DEPENDENT MALIC ENZYME, ADENOSINE-5'-TRIPHOSPHATE, TARTRONATE, ... (6 entities in total)
• Functional Keywords: allosteric regulation, energy metabolism, kinetics, oxidoreductase
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Mitochondrion matrix: P23368
• Total number of polymer chains: 4
• Total formula weight: 255424.29

Authors

Yang, Z.,Lanks, C.W.,Tong, L. (deposition date: 2002-05-15, release date: 2002-07-25, Last modification date: 2023-11-15)

• Primary citation: Yang, Z.,Lanks, C.W.,Tong, L.; Molecular Mechanism for the Regulation of Human Mitochondrial Nad(P)(+)-Dependent Malic Enzyme by ATP and Fumarate; Structure, 10:951-, 2002; PubMed: 12121650; DOI: 10.1016/S0969-2126(02)00788-8

Experimental method

X-RAY DIFFRACTION (2.2 Å)