1GUM

HUMAN GLUTATHIONE TRANSFERASE A4-4 WITHOUT LIGANDS

Summary for 1GUM

Entry DOI	10.2210/pdb1gum/pdb
Descriptor	PROTEIN (GLUTATHIONE TRANSFERASE A4-4) (2 entities in total)
Functional Keywords	glutathione transferase, oxidative stress, alkenal degradation, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: O15217
Total number of polymer chains	8
Total formula weight	205904.75
Authors	Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A. (deposition date: 1998-06-11, release date: 1999-01-27, Last modification date: 2023-08-09)
Primary citation	Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A. Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products J.Mol.Biol., 288:427-439, 1999 Cited by PubMed: 10329152 DOI: 10.1006/jmbi.1999.2697 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation