1GUL

HUMAN GLUTATHIONE TRANSFERASE A4-4 COMPLEX WITH IODOBENZYL GLUTATHIONE

Summary for 1GUL

Entry DOI	10.2210/pdb1gul/pdb
Descriptor	Glutathione S-transferase A4, GAMMA-GLUTAMYL[S-(2-IODOBENZYL)CYSTEINYL]GLYCINE (3 entities in total)
Functional Keywords	oxidative stress, alkenal degradation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: O15217
Total number of polymer chains	8
Total formula weight	210091.50
Authors	Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A. (deposition date: 1998-06-10, release date: 1999-01-27, Last modification date: 2023-09-20)
Primary citation	Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A. Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products J.Mol.Biol., 288:427-439, 1999 Cited by PubMed: 10329152 DOI: 10.1006/jmbi.1999.2697 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation