1GUL
HUMAN GLUTATHIONE TRANSFERASE A4-4 COMPLEX WITH IODOBENZYL GLUTATHIONE
Summary for 1GUL
Entry DOI | 10.2210/pdb1gul/pdb |
Descriptor | Glutathione S-transferase A4, GAMMA-GLUTAMYL[S-(2-IODOBENZYL)CYSTEINYL]GLYCINE (3 entities in total) |
Functional Keywords | oxidative stress, alkenal degradation, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: O15217 |
Total number of polymer chains | 8 |
Total formula weight | 210091.50 |
Authors | Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A. (deposition date: 1998-06-10, release date: 1999-01-27, Last modification date: 2023-09-20) |
Primary citation | Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A. Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products J.Mol.Biol., 288:427-439, 1999 Cited by PubMed: 10329152DOI: 10.1006/jmbi.1999.2697 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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