1GUL

HUMAN GLUTATHIONE TRANSFERASE A4-4 COMPLEX WITH IODOBENZYL GLUTATHIONE

1GUL の概要

• エントリーDOI: 10.2210/pdb1gul/pdb
• 分子名称: Glutathione S-transferase A4, GAMMA-GLUTAMYL[S-(2-IODOBENZYL)CYSTEINYL]GLYCINE (3 entities in total)
• 機能のキーワード: oxidative stress, alkenal degradation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: O15217
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 210091.50

構造登録者

Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A. (登録日: 1998-06-10, 公開日: 1999-01-27, 最終更新日: 2023-09-20)

• 主引用文献: Bruns, C.M.,Hubatsch, I.,Ridderstrom, M.,Mannervik, B.,Tainer, J.A.; Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products; J.Mol.Biol., 288:427-439, 1999; PubMed: 10329152; DOI: 10.1006/jmbi.1999.2697

実験手法

X-RAY DIFFRACTION (2.7 Å)