1GUA

HUMAN RAP1A, RESIDUES 1-167, DOUBLE MUTANT (E30D,K31E) COMPLEXED WITH GPPNHP AND THE RAS-BINDING-DOMAIN OF HUMAN C-RAF1, RESIDUES 51-131

1GUA の概要

• エントリーDOI: 10.2210/pdb1gua/pdb
• 分子名称: RAP1A, C-RAF1, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: oncogene protein/kinase/effector protein gtp-binding-protein, complex (gtp-binding-atp-binding), complex (gtp-binding-atp-binding) complex, complex (gtp-binding/atp-binding)
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Lipid-anchor: P62834; Cytoplasm (By similarity): P04049
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28831.89

構造登録者

Nassar, N.,Wittinghofer, A. (登録日: 1996-06-18, 公開日: 1997-01-11, 最終更新日: 2024-02-07)

• 主引用文献: Nassar, N.,Horn, G.,Herrmann, C.,Block, C.,Janknecht, R.,Wittinghofer, A.; Ras/Rap effector specificity determined by charge reversal.; Nat.Struct.Biol., 3:723-729, 1996; PubMed: 8756332; DOI: 10.1038/nsb0896-723

実験手法

X-RAY DIFFRACTION (2 Å)