1GPZ

THE CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC DOMAIN OF COMPLEMENT PROTEASE C1R

1GPZ の概要

• エントリーDOI: 10.2210/pdb1gpz/pdb
• 関連するPDBエントリー: 1APQ 1ELV
• 分子名称: COMPLEMENT C1R COMPONENT, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: hydrolase, activation, complement, innate immunity, modular structure, serine protease
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 92347.03

構造登録者

Budayova-Spano, M.,Fontecilla-Camps, J.C.,Gaboriaud, C. (登録日: 2001-11-15, 公開日: 2002-07-31, 最終更新日: 2023-12-13)

• 主引用文献: Budayova-Spano, M.,Lacroix, M.,Thielens, N.,Arlaud, G.,Fontecilla-Camps, J.C.,Gaboriaud, C.; The Crystal Structure of the Zymogen Catalytic Domain of Complement Protease C1R Reveals that a Disruptive Mechanical Stress is Required to Trigger Activation of the C1 Complex.; Embo J., 21:231-, 2002; PubMed: 11823416; DOI: 10.1093/EMBOJ/21.3.231

実験手法

X-RAY DIFFRACTION (2.9 Å)