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1GNN

HIV-1 PROTEASE MUTANT WITH VAL 82 REPLACED BY ASN (V82N) COMPLEXED WITH U89360E (INHIBITOR)

Summary for 1GNN
Entry DOI10.2210/pdb1gnn/pdb
DescriptorHIV-1 PROTEASE, N-[[1-[N-ACETAMIDYL]-[1-CYCLOHEXYLMETHYL-2-HYDROXY-4-ISOPROPYL]-BUT-4-YL]-CARBONYL]-GLUTAMINYL-ARGINYL-AMIDE (3 entities in total)
Functional Keywordsaspartic protease, hiv, mutant, inhibitor, u-89360e, hydrolase (acid protease)
Biological sourceHuman immunodeficiency virus 1
Total number of polymer chains2
Total formula weight22830.98
Authors
Hong, L.,Treharne, A.,Hartsuck, J.A.,Foundling, S.,Tang, J. (deposition date: 1996-05-04, release date: 1996-11-08, Last modification date: 2024-02-07)
Primary citationHong, L.,Treharne, A.,Hartsuck, J.A.,Foundling, S.,Tang, J.
Crystal structures of complexes of a peptidic inhibitor with wild-type and two mutant HIV-1 proteases.
Biochemistry, 35:10627-10633, 1996
Cited by
PubMed: 8718851
DOI: 10.1021/bi960481s
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

217705

건을2024-03-27부터공개중

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