1GG8

DESIGN OF INHIBITORS OF GLYCOGEN PHOSPHORYLASE: A STUDY OF ALPHA-AND BETA-C-GLUCOSIDES AND 1-THIO-BETA-D-GLUCOSE COMPOUNDS

1GG8 の概要

• エントリーDOI: 10.2210/pdb1gg8/pdb
• 分子名称: PROTEIN (GLYCOGEN PHOSPHORYLASE), ALPHA-D-GLUCOPYRANOSYL-2-CARBOXYLIC ACID AMIDE, PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
• 機能のキーワード: glycogen phosphorylase, inhibitor complex, catalytic site, design, transferase
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 98093.73

構造登録者

Watson, K.A.,Mitchell, E.P.,Johnson, L.N.,Son, J.C.,Bichard, C.J.,Orchard, M.G.,Fleet, G.W.,Oikonomakos, N.G.,Leonidas, D.D.,Kontou, M.,Papageorgiou, A.C. (登録日: 2000-07-30, 公開日: 2000-08-23, 最終更新日: 2023-08-09)

• 主引用文献: Watson, K.A.,Mitchell, E.P.,Johnson, L.N.,Son, J.C.,Bichard, C.J.,Orchard, M.G.,Fleet, G.W.,Oikonomakos, N.G.,Leonidas, D.D.,Kontou, M.,Papageorgioui, A.; Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds.; Biochemistry, 33:5745-5758, 1994; PubMed: 8180201; DOI: 10.1021/bi00185a011

実験手法

X-RAY DIFFRACTION (2.31 Å)