1GFZ

FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE

1GFZ の概要

• エントリーDOI: 10.2210/pdb1gfz/pdb
• 分子名称: GLYCOGEN PHOSPHORYLASE, PYRIDOXAL-5'-PHOSPHATE, INOSINIC ACID, ... (5 entities in total)
• 機能のキーワード: glycogen phosphorylase, glycogen metabolism, diabetes, flavopiridol, inhibitor site, transferase
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 98080.74

構造登録者

Oikonomakos, N.G.,Zographos, S.E.,Skamnaki, V.T.,Tsitsanou, K.E.,Johnson, L.N. (登録日: 2000-06-29, 公開日: 2000-07-26, 最終更新日: 2023-12-27)

• 主引用文献: Oikonomakos, N.G.,Schnier, J.B.,Zographos, S.E.,Skamnaki, V.T.,Tsitsanou, K.E.,Johnson, L.N.; Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site.; J.Biol.Chem., 275:34566-34573, 2000; PubMed: 10924512; DOI: 10.1074/jbc.M004485200

実験手法

X-RAY DIFFRACTION (2.3 Å)