1GEN

C-TERMINAL DOMAIN OF GELATINASE A

Summary for 1GEN

• Entry DOI: 10.2210/pdb1gen/pdb
• Descriptor: GELATINASE A, ZINC ION, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: hydrolase, hemopexin domain, metalloprotease, hydrolase (metalloprotease)
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Secreted, extracellular space, extracellular matrix. Isoform 2: Cytoplasm: P08253
• Total number of polymer chains: 1
• Total formula weight: 24823.01

Authors

Libson, A.M.,Gittis, A.G.,Collier, I.E.,Marmer, B.L.,Goldberg, G.G.,Lattman, E.E. (deposition date: 1995-07-19, release date: 1996-08-17, Last modification date: 2024-10-16)

Primary citation

Libson, A.M.,Gittis, A.G.,Collier, I.E.,Marmer, B.L.,Goldberg, G.I.,Lattman, E.E.
Crystal structure of the haemopexin-like C-terminal domain of gelatinase A.
Nat.Struct.Biol., 2:938-942, 1995

PubMed Abstract: The crystal structure of the haemopexin-like C-terminal domain of gelatinase A reveals that it is a four-bladed beta-propeller protein. The four blades are arranged around a channel-like opening in which Ca2+ and a Na-Cl+ ion pair are bound.

PubMed: 7583664
DOI: 10.1038/nsb1195-938

Experimental method

X-RAY DIFFRACTION (2.15 Å)