1GAV

BACTERIOPHAGE GA PROTEIN CAPSID

1GAV の概要

• エントリーDOI: 10.2210/pdb1gav/pdb
• 分子名称: BACTERIOPHAGE GA PROTEIN CAPSID (1 entity in total)
• 機能のキーワード: bacteriophage, capsid, coat protein, icosahedral virus, virus
• 由来する生物種: Enterobacteria phage GA
• タンパク質・核酸の鎖数: 45
• 化学式量合計: 613592.32

構造登録者

Tars, K.,Bundule, M.,Liljas, L. (登録日: 1997-01-28, 公開日: 1997-09-04, 最終更新日: 2024-02-07)

主引用文献

Tars, K.,Bundule, M.,Fridborg, K.,Liljas, L.
The crystal structure of bacteriophage GA and a comparison of bacteriophages belonging to the major groups of Escherichia coli leviviruses.
J.Mol.Biol., 271:759-773, 1997

PubMed Abstract: The three-dimensional structure of the small T=3 RNA bacteriophage GA has been determined at 3.4 A resolution. The structure was solved by molecular replacement, using the phage MS2 as an initial model. A comparison of the protein shells of the four related phages GA, MS2, fr and Qbeta was carried out in order to define structural features of particular importance for their assembly and specific RNA interaction. A high degree of similarity was found in the RNA binding sites, whereas larger structural differences are located in the loop regions of the coat proteins, especially in the FG loops forming 5-fold and quasi-6-fold contacts. The overall arrangement of the protein subunits in the shells of these phages is very similar, although the details of the interactions differ. The few conserved interactions are suggested to govern the subunit packing during assembly.

PubMed: 9299325
DOI: 10.1006/jmbi.1997.1214

実験手法

X-RAY DIFFRACTION (3.4 Å)