Summary for 1VM1
| Entry DOI | 10.2210/pdb1vm1/pdb |
| Related | 1SHV |
| Descriptor | BETA-LACTAMASE SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, TAZOBACTAM INTERMEDIATE, ... (6 entities in total) |
| Functional Keywords | beta-lactamase, beta-lactam hydrolase, penicillinase, detergent binding, inhibitor design, hydrolase |
| Biological source | Klebsiella pneumoniae |
| Total number of polymer chains | 1 |
| Total formula weight | 30598.88 |
| Authors | Kuzin, A.P.,Nukaga, M.,Nukaga, Y.,Hujer, A.,Bonomo, R.A.,Knox, J.R. (deposition date: 2004-08-27, release date: 2004-09-07, Last modification date: 2024-03-13) |
| Primary citation | Kuzin, A.P.,Nukaga, M.,Nukaga, Y.,Hujer, A.,Bonomo, R.A.,Knox, J.R. Inhibition of the SHV-1 beta-lactamase by sulfones: crystallographic observation of two reaction intermediates with tazobactam. Biochemistry, 40:1861-1866, 2001 Cited by PubMed: 11327849DOI: 10.1021/bi0022745 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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