1G4M

CRYSTAL STRUCTURE OF BOVINE BETA-ARRESTIN 1

1G4M の概要

• エントリーDOI: 10.2210/pdb1g4m/pdb
• 関連するPDBエントリー: 1CF1
• 分子名称: BETA-ARRESTIN1 (2 entities in total)
• 機能のキーワード: sensory transduction, alternative splicing, signaling protein
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Cytoplasm: P17870
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 88619.16

構造登録者

Schubert, C.,Han, M. (登録日: 2000-10-27, 公開日: 2001-10-03, 最終更新日: 2023-08-09)

主引用文献

Han, M.,Gurevich, V.V.,Vishnivetskiy, S.A.,Sigler, P.B.,Schubert, C.
Crystal structure of beta-arrestin at 1.9 A: possible mechanism of receptor binding and membrane Translocation.
Structure, 9:869-880, 2001

PubMed Abstract: Arrestins are responsible for the desensitization of many sequence-divergent G protein-coupled receptors. They compete with G proteins for binding to activated phosphorylated receptors, initiate receptor internalization, and activate additional signaling pathways.

PubMed: 11566136
DOI: 10.1016/S0969-2126(01)00644-X

実験手法

X-RAY DIFFRACTION (1.9 Å)