1G2B

ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48

Summary for 1G2B

• Entry DOI: 10.2210/pdb1g2b/pdb
• Descriptor: SPECTRIN ALPHA CHAIN, SULFATE ION (3 entities in total)
• Functional Keywords: capping protein, calcium-binding, duplication, sh3 domain, cytoskeleton, metal binding protein
• Biological source: Gallus gallus (chicken); More
• Cellular location: Cytoplasm, cytoskeleton: P07751
• Total number of polymer chains: 1
• Total formula weight: 7417.36

Authors

Berisio, R.,Viguera, A.R.,Serrano, L.,Wilmanns, M. (deposition date: 2000-10-18, release date: 2000-11-01, Last modification date: 2024-02-07)

Primary citation

Berisio, R.,Viguera, A.,Serrano, L.,Wilmanns, M.
Atomic resolution structure of a mutant of the spectrin SH3 domain.
Acta Crystallogr.,Sect.D, 57:337-340, 2001

PubMed Abstract: The crystal structure of an alpha-spectrin Src-homology 3 (SH3) domain mutant has been refined at 1.12 A resolution. This X-ray structure is at the highest resolution achieved so far for an SH3 domain. The structure allows the identification of a complete set of specific interactions and is useful for the elucidation of relations between structure and pH-dependent thermodynamic stability in a series of SH3 domain mutants.

PubMed: 11173498
DOI: 10.1107/S090744490001581X

Experimental method

X-RAY DIFFRACTION (1.12 Å)