1G1U

THE 2.5 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE RXRALPHA LIGAND BINDING DOMAIN IN TETRAMER IN THE ABSENCE OF LIGAND

Summary for 1G1U

Entry DOI	10.2210/pdb1g1u/pdb
Related	1FM6 1FM9 1LBD
Descriptor	RETINOIC ACID RECEPTOR RXR-ALPHA (2 entities in total)
Functional Keywords	rxralpha ligand binding domain, tetramer, absence of ligand, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus : P19793
Total number of polymer chains	4
Total formula weight	106671.43
Authors	Gampe Jr., R.T.,Montana, V.G.,Lambert, M.H.,Wisely, G.B.,Milburn, M.V.,Xu, H.E. (deposition date: 2000-10-13, release date: 2001-04-25, Last modification date: 2017-10-04)
Primary citation	Gampe Jr., R.T.,Montana, V.G.,Lambert, M.H.,Wisely, G.B.,Milburn, M.V.,Xu, H.E. Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix. Genes Dev., 14:2229-2241, 2000 Cited by PubMed: 10970886 DOI: 10.1101/gad.802300 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation