1FYR
DIMER FORMATION THROUGH DOMAIN SWAPPING IN THE CRYSTAL STRUCTURE OF THE GRB2-SH2 AC-PYVNV COMPLEX
Summary for 1FYR
Entry DOI | 10.2210/pdb1fyr/pdb |
Descriptor | GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, HEPATOCYTE GROWTH FACTOR RECEPTOR PEPTIDE (3 entities in total) |
Functional Keywords | grb2, sh2 domain, phosphopeptide, met, domain swapping, dimerization, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) More |
Cellular location | Golgi apparatus (By similarity): P29354 Membrane; Single-pass type I membrane protein: P08581 |
Total number of polymer chains | 8 |
Total formula weight | 55522.44 |
Authors | Schiering, N.,Casale, E.,Caccia, P.,Giordano, P.,Battistini, C. (deposition date: 2000-10-03, release date: 2000-12-06, Last modification date: 2023-11-15) |
Primary citation | Schiering, N.,Casale, E.,Caccia, P.,Giordano, P.,Battistini, C. Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex. Biochemistry, 39:13376-13382, 2000 Cited by PubMed: 11063574DOI: 10.1021/bi0012336 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report