1FV9

Crystal structure of human microurokinase in complex with 2-amino-5-hydroxy-benzimidazole

Summary for 1FV9

Entry DOI	10.2210/pdb1fv9/pdb
Descriptor	UROKINASE, SULFATE ION, 2-AMINO-5-HYDROXY-BENZIMIDAZOLE (3 entities in total)
Functional Keywords	plasminogen activation, blood clotting
Biological source	Homo sapiens (human)
Cellular location	Secreted: P00749
Total number of polymer chains	1
Total formula weight	27835.64
Authors	Nienaber, V. (deposition date: 2000-09-19, release date: 2000-10-18, Last modification date: 2018-01-31)
Primary citation	Hajduk, P.J.,Boyd, S.,Nettesheim, D.,Nienaber, V.,Severin, J.,Smith, R.,Davidson, D.,Rockway, T.,Fesik, S.W. Identification of novel inhibitors of urokinase via NMR-based screening. J.Med.Chem., 43:3862-3866, 2000 Cited by PubMed: 11052791 DOI: 10.1021/jm0002228 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation