1FU5
NMR STRUCTURE OF THE N-SH2 DOMAIN OF THE P85 SUBUNIT OF PI3-KINASE COMPLEXED TO A DOUBLY PHOSPHORYLATED PEPTIDE DERIVED FROM POLYOMAVIRUS MIDDLE T ANTIGEN
Summary for 1FU5
Entry DOI | 10.2210/pdb1fu5/pdb |
Related | 1FU6 |
Descriptor | PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT, DOUBLY PHOSPHORYLATED MIDDLE T ANTIGEN (2 entities in total) |
Functional Keywords | protein-peptide complex, peptide binding protein |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Host membrane; Single-pass membrane protein (Potential): P03076 |
Total number of polymer chains | 2 |
Total formula weight | 14933.47 |
Authors | Weber, T.,Schaffhausen, B.,Liu, Y.,Guenther, U.L. (deposition date: 2000-09-14, release date: 2001-02-21, Last modification date: 2022-02-23) |
Primary citation | Weber, T.,Schaffhausen, B.,Liu, Y.,Gunther, U.L. NMR structure of the N-SH2 of the p85 subunit of phosphoinositide 3-kinase complexed to a doubly phosphorylated peptide reveals a second phosphotyrosine binding site. Biochemistry, 39:15860-15869, 2000 Cited by PubMed: 11123912DOI: 10.1021/bi001474d PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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