1FPZ

CRYSTAL STRUCTURE ANALYSIS OF KINASE ASSOCIATED PHOSPHATASE (KAP) WITH A SUBSTITUTION OF THE CATALYTIC SITE CYSTEINE (CYS140) TO A SERINE

1FPZ の概要

• エントリーDOI: 10.2210/pdb1fpz/pdb
• 分子名称: CYCLIN-DEPENDENT KINASE INHIBITOR 3, SULFATE ION (3 entities in total)
• 機能のキーワード: alpha-beta sandwich, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm, perinuclear region : Q16667
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 143490.72

構造登録者

Song, H.,Hanlon, N.,Brown, N.R.,Noble, M.E.M.,Johnson, L.N.,Barford, D. (登録日: 2000-09-01, 公開日: 2001-05-09, 最終更新日: 2024-02-07)

• 主引用文献: Song, H.,Hanlon, N.,Brown, N.R.,Noble, M.E.,Johnson, L.N.,Barford, D.; Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2.; Mol.Cell, 7:615-626, 2001; PubMed: 11463386; DOI: 10.1016/S1097-2765(01)00208-8

実験手法

X-RAY DIFFRACTION (2 Å)