1FPT
THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN THE FAB FRAGMENT OF AN NEUTRALIZING ANTIBODY FOR TYPE 1 POLIOVIRUS AND ITS VIRAL EPITOPE
Summary for 1FPT
Entry DOI | 10.2210/pdb1fpt/pdb |
Descriptor | FAB FRAGMENT OF AN NEUTRALIZING ANTIBODY FOR TYPE 1 POLIOVIRUS, IGG2A-KAPPA C3 FAB (LIGHT CHAIN), IGG2A-KAPPA C3 FAB (HEAVY CHAIN), ... (4 entities in total) |
Functional Keywords | complex (antibody-pv-1 fragment), complex (antibody-pv-1 fragment) complex, complex (antibody/pv-1 fragment) |
Biological source | Human poliovirus 1 More |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03299 Cell membrane; Single-pass membrane protein (Potential): P01865 |
Total number of polymer chains | 3 |
Total formula weight | 49499.09 |
Authors | Wien, M.W.,Hogle, J.M. (deposition date: 1995-01-26, release date: 1995-03-31, Last modification date: 2024-06-05) |
Primary citation | Wien, M.W.,Filman, D.J.,Stura, E.A.,Guillot, S.,Delpeyroux, F.,Crainic, R.,Hogle, J.M. Structure of the complex between the Fab fragment of a neutralizing antibody for type 1 poliovirus and its viral epitope. Nat.Struct.Biol., 2:232-243, 1995 Cited by PubMed: 7539711DOI: 10.1038/nsb0395-232 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
Download full validation report