1FPR

CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN THE CATALYTIC DOMAIN OF SHP-1 AND AN IN VITRO PEPTIDE SUBSTRATE PY469 DERIVED FROM SHPS-1.

Summary for 1FPR

• Entry DOI: 10.2210/pdb1fpr/pdb
• Descriptor: PROTEIN-TYROSINE PHOSPHATASE 1C, PEPTIDE PY469 (2 entities in total)
• Functional Keywords: protein tyrosine phosphatase, substrate specificity, residue shift, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P29350
• Total number of polymer chains: 2
• Total formula weight: 33793.93

Authors

Yang, J.,Cheng, Z.,Niu, Z.,Zhao, Z.J.,Zhou, G.W. (deposition date: 2000-08-31, release date: 2001-03-07, Last modification date: 2021-11-03)

• Primary citation: Yang, J.,Cheng, Z.,Niu, T.,Liang, X.,Zhao, Z.J.,Zhou, G.W.; Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1.; J.Biol.Chem., 275:4066-4071, 2000; PubMed: 10660565; DOI: 10.1074/jbc.275.6.4066

Experimental method

X-RAY DIFFRACTION (2.5 Å)