1FLT
VEGF IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR
Summary for 1FLT
Entry DOI | 10.2210/pdb1flt/pdb |
Descriptor | VASCULAR ENDOTHELIAL GROWTH FACTOR, FMS-LIKE TYROSINE KINASE 1 (3 entities in total) |
Functional Keywords | complex (growth factor-transferase), flt-1 receptor, cystine knot, glycoprotein, immunoglobulin-like domain transferase, complex (growth factor-transferase) complex, complex (growth factor/transferase) |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P15692 Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted. Isoform 5: Cytoplasm (Potential). Isoform 6: Cytoplasm (Potential). Isoform 7: Cytoplasm (Potential): P17948 |
Total number of polymer chains | 4 |
Total formula weight | 44835.82 |
Authors | Wiesmann, C.,De Vos, A.M. (deposition date: 1997-11-20, release date: 1999-01-13, Last modification date: 2023-08-09) |
Primary citation | Wiesmann, C.,Fuh, G.,Christinger, H.W.,Eigenbrot, C.,Wells, J.A.,de Vos, A.M. Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor. Cell(Cambridge,Mass.), 91:695-704, 1997 Cited by PubMed: 9393862DOI: 10.1016/S0092-8674(00)80456-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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