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1FLT

VEGF IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR

Summary for 1FLT
Entry DOI10.2210/pdb1flt/pdb
DescriptorVASCULAR ENDOTHELIAL GROWTH FACTOR, FMS-LIKE TYROSINE KINASE 1 (3 entities in total)
Functional Keywordscomplex (growth factor-transferase), flt-1 receptor, cystine knot, glycoprotein, immunoglobulin-like domain transferase, complex (growth factor-transferase) complex, complex (growth factor/transferase)
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P15692
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted. Isoform 5: Cytoplasm (Potential). Isoform 6: Cytoplasm (Potential). Isoform 7: Cytoplasm (Potential): P17948
Total number of polymer chains4
Total formula weight44835.82
Authors
Wiesmann, C.,De Vos, A.M. (deposition date: 1997-11-20, release date: 1999-01-13, Last modification date: 2023-08-09)
Primary citationWiesmann, C.,Fuh, G.,Christinger, H.W.,Eigenbrot, C.,Wells, J.A.,de Vos, A.M.
Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor.
Cell(Cambridge,Mass.), 91:695-704, 1997
Cited by
PubMed: 9393862
DOI: 10.1016/S0092-8674(00)80456-0
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

217705

数据于2024-03-27公开中

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