1FLT

VEGF IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR

1FLT の概要

• エントリーDOI: 10.2210/pdb1flt/pdb
• 分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR, FMS-LIKE TYROSINE KINASE 1 (3 entities in total)
• 機能のキーワード: complex (growth factor-transferase), flt-1 receptor, cystine knot, glycoprotein, immunoglobulin-like domain transferase, complex (growth factor-transferase) complex, complex (growth factor/transferase)
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P15692; Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted. Isoform 5: Cytoplasm (Potential). Isoform 6: Cytoplasm (Potential). Isoform 7: Cytoplasm (Potential): P17948
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 44835.82

構造登録者

Wiesmann, C.,De Vos, A.M. (登録日: 1997-11-20, 公開日: 1999-01-13, 最終更新日: 2023-08-09)

• 主引用文献: Wiesmann, C.,Fuh, G.,Christinger, H.W.,Eigenbrot, C.,Wells, J.A.,de Vos, A.M.; Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor.; Cell(Cambridge,Mass.), 91:695-704, 1997; PubMed: 9393862; DOI: 10.1016/S0092-8674(00)80456-0

実験手法

X-RAY DIFFRACTION (1.7 Å)