1FIN

CYCLIN A-CYCLIN-DEPENDENT KINASE 2 COMPLEX

Summary for 1FIN

DescriptorCYCLIN-DEPENDENT KINASE 2, CYCLIN A, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywordscomplex (transferase-cyclin), cyclin, cdk, phosphorylation, complex (transferase-cyclin) complex, complex (transferase/cyclin)
Biological sourceHomo sapiens (human)
Cellular locationNucleus P20248
Total number of polymer chains4
Total molecular weight128702.36
Authors
Jeffrey, P.D.,Russo, A.A.,Pavletich, N.P. (deposition date: 1996-07-14, release date: 1997-01-27, Last modification date: 2011-07-13)
Primary citation
Jeffrey, P.D.,Russo, A.A.,Polyak, K.,Gibbs, E.,Hurwitz, J.,Massague, J.,Pavletich, N.P.
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex.
Nature, 376:313-320, 1995
PubMed: 7630397 (PDB entries with the same primary citation)
DOI: 10.1038/376313a0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers331.9%11.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report