1F8V
THE STRUCTURE OF PARIACOTO VIRUS REVEALS A DODECAHEDRAL CAGE OF DUPLEX RNA
Summary for 1F8V
Entry DOI | 10.2210/pdb1f8v/pdb |
Related | 1nov 2bbv |
Descriptor | RNA, MATURE CAPSID PROTEIN BETA, MATURE CAPSID PROTEIN GAMMA, ... (6 entities in total) |
Functional Keywords | nodavirus, coat protein, nucleoprotein, protein-rna interactions, rna duplex, rna cage, gamma polypeptide, beta-sandwich, icosahedral virus, virus-rna complex, virus/rna |
Biological source | Pariacato virus More |
Cellular location | Capsid protein beta: Virion . Peptide gamma: Virion : Q9J7Z0 Q9J7Z0 |
Total number of polymer chains | 7 |
Total formula weight | 135878.88 |
Authors | Tang, L.,Johnson, K.N.,Ball, L.A.,Lin, T.,Yeager, M.,Johnson, J.E. (deposition date: 2000-07-05, release date: 2000-12-06, Last modification date: 2024-04-03) |
Primary citation | Tang, L.,Johnson, K.N.,Ball, L.A.,Lin, T.,Yeager, M.,Johnson, J.E. The structure of pariacoto virus reveals a dodecahedral cage of duplex RNA. Nat.Struct.Biol., 8:77-83, 2001 Cited by PubMed Abstract: The 3.0 A resolution crystal structure of Pariacoto virus (PaV) reveals extensive interactions between portions of the viral RNA genome and the icosahedral capsid. Under the protein shell of the T = 3 quasi equivalent capsid lies a dodecahedral cage composed of RNA duplex that accounts for approximately 35% of the single-stranded RNA genome. The highly basic N-terminal regions (residues 7-54) of the subunits, forming pentamers (A subunits) are clearly visible in the density map and make numerous interactions with the RNA cage. The C-terminal segments (residues 394-401) of the A subunits lie in channels near the quasi three-fold axes. Electron cryo-microscopy and image reconstruction of PaV particles clearly show the dodecahedral RNA cage. PubMed: 11135676DOI: 10.1038/83089 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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