1F7A
HOW DOES A SYMMETRIC DIMER RECOGNIZE AN ASYMMETRIC SUBSTRATE? A SUBSTRATE COMPLEX OF HIV-1 PROTEASE.
Summary for 1F7A
| Entry DOI | 10.2210/pdb1f7a/pdb |
| Descriptor | POL POLYPROTEIN, CA-P2 SUBSTRATE, ACETATE ION, ... (4 entities in total) |
| Functional Keywords | capsid, substrate recognition, hydrolase |
| Biological source | Human immunodeficiency virus 1 More |
| Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03369 |
| Total number of polymer chains | 3 |
| Total formula weight | 23033.12 |
| Authors | Schiffer, C.A. (deposition date: 2000-06-26, release date: 2001-06-27, Last modification date: 2023-08-09) |
| Primary citation | Prabu-Jeyabalan, M.,Nalivaika, E.,Schiffer, C.A. How does a symmetric dimer recognize an asymmetric substrate? A substrate complex of HIV-1 protease. J.Mol.Biol., 301:1207-1220, 2000 Cited by PubMed: 10966816DOI: 10.1006/jmbi.2000.4018 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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