1F7A

HOW DOES A SYMMETRIC DIMER RECOGNIZE AN ASYMMETRIC SUBSTRATE? A SUBSTRATE COMPLEX OF HIV-1 PROTEASE.

1F7A の概要

• エントリーDOI: 10.2210/pdb1f7a/pdb
• 分子名称: POL POLYPROTEIN, CA-P2 SUBSTRATE, ACETATE ION, ... (4 entities in total)
• 機能のキーワード: capsid, substrate recognition, hydrolase
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03369
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 23033.12

構造登録者

Schiffer, C.A. (登録日: 2000-06-26, 公開日: 2001-06-27, 最終更新日: 2023-08-09)

• 主引用文献: Prabu-Jeyabalan, M.,Nalivaika, E.,Schiffer, C.A.; How does a symmetric dimer recognize an asymmetric substrate? A substrate complex of HIV-1 protease.; J.Mol.Biol., 301:1207-1220, 2000; PubMed: 10966816; DOI: 10.1006/jmbi.2000.4018

実験手法

X-RAY DIFFRACTION (2 Å)