1F3M

CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE KINASE PAK1

Summary for 1F3M

DescriptorSERINE/THREONINE-PROTEIN KINASE PAK-ALPHA, IODIDE ION, ... (4 entities in total)
Functional Keywordskinase domain, autoinhibitory fragment, homodimer, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm  Q13153 Q13153
Total number of polymer chains4
Total molecular weight88460.21
Authors
Lei, M.,Lu, W.,Meng, W.,Parrini, M.-C.,Eck, M.J.,Mayer, B.J.,Harrison, S.C. (deposition date: 2000-06-05, release date: 2000-06-29, Last modification date: 2017-02-01)
Primary citation
Lei, M.,Lu, W.,Meng, W.,Parrini, M.C.,Eck, M.J.,Mayer, B.J.,Harrison, S.C.
Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch.
Cell(Cambridge,Mass.), 102:387-397, 2000
PubMed: 10975528 (PDB entries with the same primary citation)
DOI: 10.1016/S0092-8674(00)00043-X
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.255572.4%3.4%14.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution