1EZX
CRYSTAL STRUCTURE OF A SERPIN:PROTEASE COMPLEX
Summary for 1EZX
Entry DOI | 10.2210/pdb1ezx/pdb |
Descriptor | ALPHA-1-ANTITRYPSIN, TRYPSIN, ... (4 entities in total) |
Functional Keywords | protease-inhibitor complex, serpin, alpha-1-antitrypsin, trypsin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted. Short peptide from AAT: Secreted, extracellular space, extracellular matrix: P01009 P01009 Secreted, extracellular space: P00760 |
Total number of polymer chains | 3 |
Total formula weight | 67277.58 |
Authors | Huntington, J.A.,Carrell, R.W. (deposition date: 2000-05-12, release date: 2000-10-25, Last modification date: 2011-07-13) |
Primary citation | Huntington, J.A.,Read, R.J.,Carrell, R.W. Structure of a serpin-protease complex shows inhibition by deformation. Nature, 407:923-926, 2000 Cited by PubMed: 11057674DOI: 10.1038/35038119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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